Required Treatment For Melasma Clinic in Dhankawadi.Katraj, Ambegaon, Pune? Best Treatment For Melasma Clinic in Pune? Jiya's Skin Hair and Laser Clinic is the Best Treatment For Melasma Clinic in Dhankawadi, Katraj, Ambegaon, Pune. What is the most effective treatment for melasma? The most commonly used treatments for melasma are skin lightening medications that are applied topically. These include medications such as hydroquinone, azelaic acid, kojic acid, niacinamide, cysteamine, rucinol, and tranexamic acid.